MDCAT XI Biology Immunity Online Test-2

846

Created on July 16, 2025 By

📚 Test Details

Subject: Biology
Class: 1st year / XI
Chapter: Immunity
Test: 2
Book: Sindh Textbook
Total No. Of MCQs: 50 MCQs
Time Allowed: 50 Minutes

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1 / 50

1. How many lobes does a mature neutrophil have?

a) 2–5

b) 3–5

c) 5–8

d) 7–9

2 / 50

2. Which layer of skin is made up of dead cells and keratin?

a) Epidermis

b) Dermis

c) Hypodermis

d) Epithelial

3 / 50

3. What is the largest organ of the human body?

a) Liver

b) Skin

c) Kidney

d) Lung

4 / 50

4. Tears contribute to human immunity by acting as a:

a) Physical barrier

b) Biochemical barrier

c) Structural barrier

d) Incomplete barrier

5 / 50

5. Which of the following is a component of the second line of defense that is non-specific in nature?

a) Phagocytosis

b) NK cells

c) Fever

d) All of the above

6 / 50

6. Humoral immunity is due to:

a) T cells

b) B cells

c) Dendritic cells

d) Monocytes and neutrophils

7 / 50

7. The thymus gland is involved in the maturation of:

a) T cells

b) B cells

c) Neutrophils

d) Macrophages

8 / 50

8. Which cell has CD4, CD, and TCR receptors on its surface?

a) Th

b) Ts

c) Tc

d) Tm

9 / 50

9. Lymphocytes constitute what percentage of circulating WBCs?

a) 20–40%

b) 80–90%

c) 60–80%

d) 50–60%

10 / 50

10. Which of the following is NOT correct?

a) B cells differ from T cells in mode of activation

b) T cells secrete antibodies

c) Cell-mediated immunity is mainly due to T cells

d) All of the above

11 / 50

11. How many types of vaccines are there?

a) Four

b) Three

c) Many

d) Two

12 / 50

12. The global alarm system of our body's immune system is:

a) MHC II

b) MHC I

c) MHC III

d) T helper cells

13 / 50

13. MHC II molecules are present on:

a) Macrophages

b) Dendritic cells

c) B cells

d) All of the above

14 / 50

14. Which of the following is an example of passive artificial immunity?

a) Clinical infection

b) Purified antigen vaccine

c) Breast milk

d) Immune cells from another individual

15 / 50

15. Vaccination is an example of which type of immunity?

a) Active natural

b) Active artificial

c) Passive natural

d) Passive artificial

16 / 50

16. Which of the following is an example of active natural immunity?

a) Vaccination

b) Through the placenta

c) Inoculation of immune serum

d) Infection

17 / 50

17. Antibodies are secreted by:

a) T cells

b) B cells

c) Plasma cells

d) Macrophages

18 / 50

18. Which of the following is correct?

a) MHC I has two alpha and two beta chains

b) MHC II is composed of three alpha subunits

c) MHC I is composed of beta microglobulin and three alpha subunits

d) MHC I is composed of two alpha units and two beta microglobulins

19 / 50

19. The immune system of a vertebrate can produce how many different antibodies?

a) Millions

b) Billions

c) Few

d) Less than 10

20 / 50

20. Which cell is referred to as a "serial killer"?

a) NK cell

b) Neutrophil

c) Tc cell

d) Macrophage

21 / 50

21. MHC I molecules are present on:

a) All nucleated cells

b) RBCs

c) Dendritic cells

d) All of the above

22 / 50

22. Which of the following is a salicylate?

a) Aspirin

b) Paracetamol

c) Ibuprofen

d) None of the above

23 / 50

23. Although fever is beneficial, it has harmful effects such as:

a) Dehydration

b) Causing death of body cells

c) Body ache

d) All of the above

24 / 50

24. Prostaglandins involved in thermogenesis are produced by the:

a) Medulla

b) Brain stem

c) Hypothalamus

d) Thalamus

25 / 50

25. Which of the following is NOT a pyrogen?

a) IL-1

b) TNF

c) IL-6

d) IL-12

26 / 50

26. Which of the following is correct regarding substances that cause fever?

a) May be endogenous

b) Released into the blood by active macrophages

c) May be exogenous

d) All of the above

27 / 50

27. Substances that induce fever are called:

a) Pyrogens

b) Pyroxene

c) Cytokines

d) Interleukins

28 / 50

28. Pyrexia is a:

a) Disease

b) Symptom

c) Physical damage

d) Tumor

29 / 50

29. Which of the following mainly functions in phagocytosis?

a) B cells

b) Neutrophils

c) Memory cells

d) T cells

30 / 50

30. When tissue damage occurs, histamine dilates blood vessels and attracts:

a) Neutrophils

b) Macrophages

c) Plasma cells

d) A and B

31 / 50

31. Which of the following is NOT a characteristic of acute inflammation?

a) Redness

b) Pain

c) Swelling

d) Granuloma formation

32 / 50

32. In the presence of an antigen, complement proteins are activated; some damage cell membranes, while others attract cells such as:

a) Neutrophils

b) Macrophages

c) Mast cells

d) All of the above

33 / 50

33. Which of the following is correct?

a) T cells mature in the bone marrow

b) B cells mature in the thymus

c) B cells mature in the blood

d) B cells mature in the bone marrow

34 / 50

34. Which of the following is correct?

a) NK cells are lymphoid in lineage

b) Tc cells are myeloid in lineage

c) Both are myeloid in lineage

d) Both are lymphoid in lineage

35 / 50

35. Which term refers to the ability of a substance to damage or destroy target cells?

a) Phagocytosis

b) Cytotoxicity

c) Inflammation

d) Lysis

36 / 50

36. Dendritic cells migrate to secondary lymphoid organs such as:

a) Tonsils

b) Spleen

c) Peyer's patches

d) All of the above

37 / 50

37. Dendritic cells and macrophages present antigens to:

a) B cells

b) Plasma cells

c) T cells

d) Neutrophils

38 / 50

38. Macrophages adapt to specific tissue conditions and are called Kupffer cells in the:

a) Lungs

b) Liver

c) Kidney

d) Brain

39 / 50

39. What is the lifespan of a monocyte?

a) 2–5 days

b) 2–8 days

c) 5–10 days

d) 8–12 days

40 / 50

40. Neutrophils can recognize various bacterial molecules such as:

a) Peptidoglycan

b) Lipopeptide

c) Flagellum

d) All of the above

41 / 50

41. Neutrophils make up what percentage of total leukocytes?

a) 2–8%

b) 2–5%

c) 50–70%

d) 50–80%

42 / 50

42. Which is the most abundant type of white blood cell?

a) Monocyte

b) Macrophage

c) Dendritic cell

d) Neutrophils

43 / 50

43. The mucosa provides a biochemical barrier through its mucus, which contains many:

a) Glycoprotein molecules

b) Antimicrobial peptides

c) Polypeptide chains

d) Conjugated molecules

44 / 50

44. Which of the following statements about the hypodermis is NOT correct?

a) Connects the skin to underlying muscles and bones

b) Contains sweat and sebaceous glands

c) Serves as an insulating layer

d) All of the above

45 / 50

45. Which of the following consists of living cells, blood vessels, and nerves?

a) Dermis

b) Epidermis

c) Hypodermis

d) Endodermis

46 / 50

46. Langerhans cells are:

a) Skin-resident macrophages

b) T cells

c) B cells

d) Dendritic cells

47 / 50

47. Which is the outermost layer of the skin that lacks blood supply?

a) Epidermis

b) Dermis

c) Hypodermis

d) Hyerdermis

48 / 50

48. What is the function of skin?

a) To provide protection

b) Acts as a reservoir for the synthesis of vitamin D

c) Serves as a barrier

d) All of the above

49 / 50

49. Which of the following statements about inflammation is correct?

a) Non-specific response

b) It is part of the first line of defense

c) It belongs to the adaptive immune system

d) none of these

50 / 50

50. Which of the following acts as both a physical and biochemical barrier?

a) Skin

b) Saliva

c) Mucous

d) Tears

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MDCAT XI Biology Immunity Online Test-2

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